About FAIR PBK Inspector

Making PBK models interoperable and reusable

Version v0.5.0

Key Features

This tool assists in creating interoperable and reusable PBK models following the FAIR PBK Standard. It contains features for:

Semantic annotation

Annotate model components with semantic ontology terms.

Annotation of units

Annotate and validate units across model elements.

Model validation

Validate models against the FAIR PBK standard.

Model visualisation

Generate model diagrams for documentation.

Export templates

Export templates for annotation and parametrisation.

FAIR PBK Standard

The FAIR PBK Standard is an open exchange standard for representing physiologically based kinetic (PBK) models. It combines the use of the Systems Biology Markup Language (SBML) with specific guidelines for annotation of units and model elements, leveraging domain-specific ontologies such as PBPKO, ChEBI, and the NCBI Taxonomy. With this, it ensures (semantic) consistency and enables interoperability, supporting the consistent reuse of models across software platforms, modeling environments, and application domains.

View Specification

Development

This tool is developed by Biometris, Wageningen University & Research in collaboration with partners from the European Partnership for the Assessment of Risks from Chemicals (PARC).

Funding

This tool was developed in the framework of the European Partnership for the Assessment of Risks from Chemicals (PARC) and has received funding from the European Union's Horizon Europe research and innovation programme under Grant Agreement No 101057014 with co-funding from the authors' organizations. Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the Health and Digital Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.

For more information and resources, visit the FAIR PBK Standard webpage.